Dr Michelle Linterman
Programme Leader - Linterman Laboratory
BBmedSc(Hons) (VUW), MA (Cantab), PhD (ANU)
Michelle Linterman's research focus is on how different cell types collaborate in the germinal centre to generate a robust antibody response following vaccination and infection. Her team’s work combines research in mice, with human studies to enable us to deliver mechanistic insight into the germinal centre response that is of direct relevance to human health.
See Michelle's Google Scholar profile here.
Related news
New research group taking aim at ageing immunity
23 June 2025
Dr Michelle Linterman: Asking the age-old question
30 April 2025
Kia Niwha Leader Fellowship for Malaghan vaccine researcher
6 May 2024
Malaghan research collaboration: Strengthening the immune system in ageing populations
29 April 2024
International collaboration to crack the code on the ageing immune system
31 May 2023
Malaghan visiting researcher: Dr Michelle Linterman
27 January 2023
Publications
2025
Pankhurst TE, Linterman MA (2025). Highlights of 2024: Advances in Germinal Centers. Immunol Cell Biol. 103(6):492-495.
Guillaume SM, Foster WS, San Martín Molina I, Watson EM, Innocentin S, Kennedy GM, Denton AE*, Linterman MA*. *Joint senior authors (2025). Lung B cells in ectopic germinal centers undergo affinity maturation. Proc Natl Acad Sci U S A. 2025 Apr 8;122(14):e2416855122.
2023
Lee JL, Innocentin S, Silva-Cayetano A, Guillaume SM, Linterman MA (2023). B Cells from Aged Mice Do Not Have Intrinsic Defects in Affinity Maturation in Response to Immunization. Journal of Immunology. 2023 Nov 15.
Silva-Cayetano A, Fra-Bido S, Robert PA, Innocentin S, Burton AR, Watson EM, Lee JL, Webb LMC, Foster WS, McKenzie RCJ, Bignon A, Vanderleyden I, Alterauge D, Lemos JP, Carr EJ, Hill DL, Cinti I, Balabanian K, Baumjohann D, Espeli M, Meyer-Hermann M, Denton AE, Linterman MA. (2023). Spatial dysregulation of T follicular helper cells impairs vaccine responses in aging. Nature Immunology.
2022
Burton AR, Guillaume SM, Foster WS, Wheatley AK, Hill DL, Carr EJ*, Linterman MA*. *Joint senior authors (2022). The memory B cell response to influenza vaccination is impaired in older persons. Cell Reports. 2022 Nov 8;41(6):111613.
Denton AE, Dooley J, Cinti I, Silva-Cayetano A, Fra-Bido S, Innocentin S, Hill DL, Carr EJ, McKenzie ANJ, Liston A and Linterman MA. (2022). Targeting TLR4 during vaccination boosts MAdCAM-1+ lymphoid stromal cell activation and promotes GC responses in aging. Science Immunology. 2022 May 6;7(71):eabk0018.
2021
Silva-Cayetano A†, Foster WS†, Innocentin S†, Belij-Rammerstorfer S, Spencer AJ, Burton OT, Fra-Bidó S, Lee JL, Thakur N, Conceicao C, Wright D, Barett J, Evans-Bailey N, Noble C, Bailey D, Liston A, Gilbert SC, Lambe T*, Linterman MA*. *Joint senior authors, †Joint first authors. (2021) A booster dose enhances immunogenicity of the COVID-19 vaccine candidate ChAdOx1 nCoV-19 in aged mice. Med. 2021 Mar 12;2(3):243-262.e8.