Dr Rubio Reyes received her PhD in Microbiology and Genetics from Massey University, under the supervision of Professor Bernd Rehm. In her PhD she studied the production and use of bacterially-derived polyester beads as a vaccine delivery system for Mycobacterium tuberculosis antigens and immune modulators. Her research demonstrated the potential of beads displaying the antigen Rv1626 to protect mice in an experimental model of tuberculosis infection. Later she worked as a research scientist at a small start-up company developing mastitis diagnostic tests.
Dr Rubio Reyes is a Postdoctoral Research Fellow in the Hermans Laboratory.
"CAR-T cell therapy is only effective in the treatment of haematological cancers and when it targets antigens that are homogenously produced on malignant cells. I am interested in investigating CAR modifications to facilitate their use in other settings and finding new biomarkers to design CARs targeting solid tumours. After a number of years acquiring experience in areas like molecular biology and microbiology, I am looking forward to understanding the immune system in order to develop new vaccines and therapies.
"My project focuses on addressing the hurdles that impede the use of CAR-T cell therapy for the treatment of solid tumours. We will also incorporate a safety off-switch into the CARs as a mechanism to manage their toxicity."
Malaghan researcher named as KiwiNet Emerging Innovator
18 September 2023
Improving CAR T-cell therapy to target solid tumours
23 May 2022
Our Changing World - the future of cancer treatment
31 March 2022
In focus: Overcoming hurdles facing CAR T-cell therapy
19 January 2022
Building better CAR T-cell technology
3 May 2021