Jeffry completed his PhD at the School of Chemical Sciences, the University of Auckland, under the supervisions of A/Prof Robert F. Anderson and Prof Laurence Melton in 2018. His thesis investigated the molecular mechanisms by which bioavailable phenolic metabolites derived from the extensive metabolism of blueberry polyphenols could alleviate oxidative stress-induced endothelial dysfunction. Following his PhD training, he worked at the Centre for Free Radical Research, the University of Otago Christchurch, where he studied the relationships between the levels of a variety of protein and small-molecule markers of oxidative stress, with aspects of human health and development.
Jeffry is a postdoctoral research fellow in the Gasser Laboratory.
"The limited bioavailability and extensive metabolism of many dietary compounds have piqued my interests in investigating how different metabolites generated during the first-pass and microbial metabolisms of these compounds can benefit immune cell function. I am particularly interested in better understanding how these metabolites could impact immune tolerance towards normal intestinal flora, while simultaneously boosting responses against pathogens and other stimuli deleterious to immune homeostasis."
Study finds a high-fibre diet can improve immune response to vaccines
18 November 2021
Malaghan Institute seeking volunteers for clinical study to investigate the effect of Chinese herbal medicine on human health
11 June 2021
Gut health - new frontiers in immunology
3 May 2021
MAIT cells and Mānuka honey – scientists uncover novel antibacterial mechanism
29 July 2020
Cait A, Mooney A, Poyntz H, Shortt N, Jones A, Gestin A, Gell K, Grooby A, O’Sullivan D, Tang JS, Young W, Thayabaran D, Sparks J, Ostapowicz T, Tay A, Poppitt SD, Elliott S, Wakefield G, Parry-Strong A, Ralston J, Beasley R, Weatherall M, Braithwaite I, Forbes-Blom E and Gasser O (2021). Potential Association Between Dietary Fibre and Humoral Response to the Seasonal Influenza Vaccine. Front. Immunol. 12:765528
Tang JS, Cait A, Li Y, Abolins-Thompson H, Gell K, Herst PM, O'Sullivan D, Gasser O (2021). Practical Approach To Explore the Effects of Polyphenols on Aryl Hydrocarbon Receptor Regulated Immune Function. J Agric Food Chem. 69(31):8625-8633
Gasser O, Tang J, Cait A (2021). Commentary on "properties and reactivity of the folic acid and folate photoproduct 6-formylpterin" by Goossens et al. [Free radic. Biol. Med. (2021) May 6;S0891-5849(21)00283-5]. Free Radic Biol Med. 2021 Jul 8:S0891-5849(21)00405-6