Dr Minnell completed his PhD at Imperial College London studying virus-host interactions in the context of Human T-cell Lymphotropic Virus 1 infection from a structural and molecular perspective.
His focus is now on mRNA vaccine development, investigating novel vaccines to induce tissue-resident memory T-cell populations in the liver.
Dr Minnell is postdoctoral research fellow in the Hermans Laboratory.
"My work is centred around creating mRNA vaccines that drive tissue-resident memory T-cell formation in the liver. The presence of issue-resident memory T-cell populations in the tissue where pathogens replicate and infect is associated with superior immune protection from disease, and we are currently aiming to apply these principles to liver-stage pathogens such as malaria and the hepatitis B virus."
Farrand K, Holz LE, Ferrer-Font L, Wilson MD, Ganley M, Minnell JJ, Tang CW, Painter GF, Heath WR, Hermans IF, Burn OK (2022). Using Full-Spectrum Flow Cytometry to Phenotype Memory T and NKT Cell Subsets with Optimized Tissue-Specific Preparation Protocols. Curr Protoc. 2(7):e482.