Dr Alissa Cait received her PhD from the University of British Columbia in Canada in the department of Microbiology and Immunology under the supervision of Dr William Mohn. Her thesis looked at how metabolites derived from the microbiome impact the development of atopic disease.
Alissa is part of the Gasser Laboratory.
Research interests
"For every human cell in our body we are host to at least one microbial cell. These microbes are critical for our immune-system development. My research interests are in better understanding how our microbiome interacts with our immunes system and how we can modify this interaction to promote health."
Related news
Location, location, location: study finds where MAIT cells live may determine their role in allergic disease
12 February 2024
In Focus: Cultivating a healthy, diverse and blooming microbiome
12 April 2023
Investigating the impact of dietary fibre on infant health
1 November 2022
Study shows link between prenatal antibiotic exposure and allergic diseases
18 July 2022
Study finds a high-fibre diet can improve immune response to vaccines
18 November 2021
Gut health - new frontiers in immunology
3 May 2021
Publications
2024
2023
Tang JS, Stephens R, Li Y, Cait A, Gell K, Faulkner S, Grooby A, Herst PM, O'Sullivan D, Gasser O (2023). Polyphenol and glucosinolate-derived AhR modulators regulate GPR15 expression on human CD4+ T cells. J Nutr Biochem. 122:109456
Mules TC, Lavender B, Maclean K, Vacca F, Noble SL, Yumnam B, Te Kawa T, Cait A, Tang J, O'Sullivan D, Gasser O, Stanley J, Le Gros G, Camberis M, Inns S (2023). Controlled Hookworm Infection for Medication-free Maintenance in Patients with Ulcerative Colitis: A Pilot, Double-blind, Randomized Control Trial. Inflamm Bowel Dis. 2023 Jun 15
2022
Tang JS, Cait A, White RM, Arabshahi HJ, O’Sullivan D and Gasser O (2022). MR1-dependence of unmetabolized folic acid side-effects. Front. Immunol. 13:946713
Cait A, Wedel A, Arntz JL, Duinkerken J, Datye S, Cait J, Alhasan MM, Conrad ML (2022). Prenatal antibiotic exposure, asthma and the atopic march: A systematic review and meta-analysis. Allergy. 2022 Jun 11
Woods K, Cait A, Gell K, Naidoo K, Brown C, Carpenter E, Gasser O (2022). Goat milk-derived lipids restrain NKT cell-dependent eosinophilic inflammation in a murine model of atopic dermatitis. J Invest Dermatol. 14:S0022-202X(22)00200-7
Cait J, Cait A, Scott RW, Winder CB, Mason GJ (2022). Conventional laboratory housing increases morbidity and mortality in research rodents: results of a meta-analysis. BMC Biol. 20(1):15
2021
Cait A, Mooney A, Poyntz H, Shortt N, Jones A, Gestin A, Gell K, Grooby A, O’Sullivan D, Tang JS, Young W, Thayabaran D, Sparks J, Ostapowicz T, Tay A, Poppitt SD, Elliott S, Wakefield G, Parry-Strong A, Ralston J, Beasley R, Weatherall M, Braithwaite I, Forbes-Blom E and Gasser O (2021). Potential Association Between Dietary Fibre and Humoral Response to the Seasonal Influenza Vaccine. Front. Immunol. 12:765528
Tang JS, Cait A, Li Y, Abolins-Thompson H, Gell K, Herst PM, O'Sullivan D, Gasser O (2021). Practical Approach To Explore the Effects of Polyphenols on Aryl Hydrocarbon Receptor Regulated Immune Function. J Agric Food Chem. 69(31):8625-8633
Gasser O, Tang J, Cait A (2021). Commentary on "properties and reactivity of the folic acid and folate photoproduct 6-formylpterin" by Goossens et al. [Free radic. Biol. Med. (2021) May 6;S0891-5849(21)00283-5]. Free Radic Biol Med. 2021 Jul 8:S0891-5849(21)00405-6
Naidoo K, Woods K, Pellefigues C, Cait A, O'Sullivan D, Gell K, Marshall AJ, Anderson RJ, Li Y, Schmidt A, Prasit K, Mayer JU, Gestin A, Hermans IF, Painter G, Jacobsen EA, Gasser O (2021). MR1-dependent immune surveillance of the skin contributes to pathogenesis and is a photobiological target of UV light therapy in a mouse model of atopic dermatitis. Allergy. 76(10):3155-3170