Dr O’Sullivan completed his PhD at Te Herenga Waka—Victoria University of Wellington, under the supervision of Professor Anne La Flamme. He has since undertaken Postdoctoral Fellowships at Washington University in St Louis, USA and at the Max Planck Institute of Immunology and Epigenetics, Germany, within the Lab of Professor Erika Pearce.
Dr O’Sullivan is currently a Senior Research Fellow working in the Gasser Laboratory.
"My research has always been broadly focused around identifying ways we can optimise immune responses. I have a particular interest in exploring how we can use metabolism to influence the function and fate of immune cells, for the benefit of human health."
Clinical study investigating the impact of dietary fibre on type-2 diabetes
20 September 2022
Study finds a high-fibre diet can improve immune response to vaccines
18 November 2021
Marsden Fund for research on the impact of fever on immune cell function
3 November 2021
Gut health - new frontiers in immunology
3 May 2021
MAIT cells and Mānuka honey – scientists uncover novel antibacterial mechanism
29 July 2020
Dr David O’Sullivan: the immune system and metabolic health
15 July 2020
Tang JS, Cait A, White RM, Arabshahi HJ, O’Sullivan D and Gasser O (2022). MR1-dependence of unmetabolized folic acid side-effects. Front. Immunol. 13:946713
Cait A, Mooney A, Poyntz H, Shortt N, Jones A, Gestin A, Gell K, Grooby A, O’Sullivan D, Tang JS, Young W, Thayabaran D, Sparks J, Ostapowicz T, Tay A, Poppitt SD, Elliott S, Wakefield G, Parry-Strong A, Ralston J, Beasley R, Weatherall M, Braithwaite I, Forbes-Blom E and Gasser O (2021). Potential Association Between Dietary Fibre and Humoral Response to the Seasonal Influenza Vaccine. Front. Immunol. 12:765528
Tang JS, Cait A, Li Y, Abolins-Thompson H, Gell K, Herst PM, O'Sullivan D, Gasser O (2021). Practical Approach To Explore the Effects of Polyphenols on Aryl Hydrocarbon Receptor Regulated Immune Function. J Agric Food Chem. 69(31):8625-8633
Naidoo K, Woods K, Pellefigues C, Cait A, O'Sullivan D, Gell K, Marshall AJ, Anderson RJ, Li Y, Schmidt A, Prasit K, Mayer JU, Gestin A, Hermans IF, Painter G, Jacobsen EA, Gasser O (2021). MR1-dependent immune surveillance of the skin contributes to pathogenesis and is a photobiological target of UV light therapy in a mouse model of atopic dermatitis. Allergy. 76(10):3155-3170