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Dr David O'Sullivan

Dr David O’Sullivan completed his PhD at Te Herenga WakaVictoria University of Wellington, under the supervision of Professor Anne La Flamme. He has since undertaken Postdoctoral Fellowships at Washington University in St Louis, USA and at the Max Planck Institute of Immunology and Epigenetics, Germany, within the Lab of Professor Erika Pearce.  

David is currently a senior research fellow working in the Gasser Laboratory.

Research interests

"My research has always been broadly focused around identifying ways we can optimise immune responses. I have a particular interest in exploring how we can use metabolism to influence the function and fate of immune cells, for the benefit of human health."



Herst P, Carson G, Lewthwaite D, Eccles D, Schmidt A, Wilson A, Grasso C, O’Sullivan D, Neuzil J, McConnell M, Berridge M (2024). Residual OXPHOS is required to drive primary and metastatic lung tumours in an orthotopic breast cancer model. Frontiers in Oncology. May 2024

Cait A, Woods K, Naidoo K, Gell K, Schmidt A, Jackson R, Grooby A, O'Sullivan D, Gasser O (2024). Tissue-specific contribution of mucosal-associated invariant T cells to allergic airway inflammation. Allergy. 2024 Jan 25


Tang JS, Stephens R, Li Y, Cait A, Gell K, Faulkner S, Grooby A, Herst PM, O'Sullivan D, Gasser O (2023). Polyphenol and glucosinolate-derived AhR modulators regulate GPR15 expression on human CD4+ T cells. J Nutr Biochem. 122:109456

Mules TC, Lavender B, Maclean K, Vacca F, Noble SL, Yumnam B, Te Kawa T, Cait A, Tang J, O'Sullivan D, Gasser O, Stanley J, Le Gros G, Camberis M, Inns S (2023). Controlled Hookworm Infection for Medication-free Maintenance in Patients with Ulcerative Colitis: A Pilot, Double-blind, Randomized Control Trial. Inflamm Bowel Dis. 2023 Jun 15


Tang JS, Cait A, White RM, Arabshahi HJ, O’Sullivan D and Gasser O (2022). MR1-dependence of unmetabolized folic acid side-effects. Front. Immunol. 13:946713


Cait A, Mooney A, Poyntz H, Shortt N, Jones A, Gestin A, Gell K, Grooby A, O’Sullivan D, Tang JS, Young W, Thayabaran D, Sparks J, Ostapowicz T, Tay A, Poppitt SD, Elliott S, Wakefield G, Parry-Strong A, Ralston J, Beasley R, Weatherall M, Braithwaite I, Forbes-Blom E and Gasser O (2021). Potential Association Between Dietary Fibre and Humoral Response to the Seasonal Influenza Vaccine. Front. Immunol. 12:765528

Tang JS, Cait A, Li Y, Abolins-Thompson H, Gell K, Herst PM, O'Sullivan D, Gasser O (2021). Practical Approach To Explore the Effects of Polyphenols on Aryl Hydrocarbon Receptor Regulated Immune Function. J Agric Food Chem. 69(31):8625-8633

Naidoo K, Woods K, Pellefigues C, Cait A, O'Sullivan D, Gell K, Marshall AJ, Anderson RJ, Li Y, Schmidt A, Prasit K, Mayer JU, Gestin A, Hermans IF, Painter G, Jacobsen EA, Gasser O (2021). MR1-dependent immune surveillance of the skin contributes to pathogenesis and is a photobiological target of UV light therapy in a mouse model of atopic dermatitis. Allergy. 76(10):3155-3170