Arthritis & Inflammation Group Publications

Chia EW, Grainger R, Harper JL (2008) Colchicine suppresses neutrophil superoxide production in a murine model of gouty arthritis: a rationale for use of low dose colchicine. Br J Pharmacol, 153:1288-95

Grainger R, Harrison A (2008) Infliximab in the treatment of Ankylosing Spondylitis. Biolog Targ Ther, (in press)

Grainger R, Taylor W (2008) Establishing outcome domains for evaluating treatment of acute and chronic gout. Curr Opin Rheumatol, 20:173-8 

Taylor WJ, Schumacher HR Jr, Baraf HS, Chapman P, Stamp L, Doherty M, McQueen FM, Dalbeth N, Schlesinger N, Furst DE, Vazquez-Mellado J, Becker MA, Kavanaugh A, Louthrenoo W, Bardin T, Khanna D, Simon LS, Yamanaka H, Choi HK, Zeng X, Strand V, Grainger R, Clegg D, Singh JA, Diaz-Torne C, Boers M, Gow P, Barskova V (2008) A modified Delphi exercise to determine the extent of consensus with OMERACT outcome domains for studies of acute and chronic gout. Ann Rheum Dis, 67:888-91; Epub 2007 Nov 29

Harper JL, Larsen D, Severn W, Singh G (2007) Synthetic molecules having immune activity. NZ Patent awarded 31st May 2007: Patented New Zealand No. 529603/533245

Pearce AN, Chia EW, Berridge MV, Clark GR, Harper JL, Larsen L, Maas EW, Page MJ, Perry NB, Webb VL, Copp BR (2007) Anti-inflammatory thiazine alkaloids isolated from the New Zealand ascidian Aplidium sp.: inhibitors of the neutrophil respiratory burst in a model of gouty arthritis. J Nat Prod, 70:936-40

Pearce AN, Chia EW, Berridge MV, Maas EW, Page MJ, Webb VL, Harper JL, Copp BR (2007) E/Z-rubrolide O, an anti-inflammatory halogenated furanone from the New Zealand ascidian Synoicum n. sp. J Nat Prod 70:111-3

Sansom CE, Larsen L, Perry NB, Berridge MV, Chia EW, Harper JL, Webb VL (2007) An anti-proliferative bis-prenylated quinone from the New Zealand brown alga Perithalia capillaris. J Nat Prod, 70:2042-4 

Taylor WJ, Schumacher HR Jr, Singh JA, Grainger R, Dalbeth N (2007) Assessment of outcome in clinical trials of gout - a review of current measures. Rheumatology (Oxford), 46:1751-6

Ainge GD, Hudson J, Larsen DS, Painter GF, Gill GS, Harper JL (2006) Phosphatidylionsitol mannosides: synthesis and suppression of allergic airway disease. Bioorg Med Chem, 14:5632-42

Copp BR, Pearce AN, Denny WA, Berridge MV, Harper JL, Perry NB, Larsen L, Godfrey CA "Anti-inflammatory compounds" Patent PCT/NZ2005/000246, published as WO06/031134 on 23 March 2006

Harper JL, Larsen D, Severn W, Singh G "Synthetic molecules having immune activity", NZ 529603/533245, Patent Acceptance, December 2006

McNamara CE, Larsen L, Perry NB, Harper JL, Berridge MV, Chia EW, Kelly M, Webb VL (2005) Anti-inflammatory sesquiterpene-quinones from the New Zealand sponge Dysidea cf. cristagalli. J Nat Prod, 68:1431-3

Sayers I, Severn W, Scanga C, Hudson J, LeGros G, Harper JL (2004) Suppression of allergic airway disease using mycobacterial lipoglycans. J Allergy Clin Immunol. 114:302-9

Harper JL (2004) Can bacteria fight asthma? Editors choice- J Allerg Clinic Immunol, 114:212

Sayers I, LeGros G, Harper JL (2003) From hygiene hypothesis to novel allergic asthma therapies. Current Medicinal Chemistry 2:143-55

Beasley R, Shirtcliffe P, Holt S, Harper JL, Le Gros G (2002) Mycobacterium-based vaccines for the prevention of allergic disease - a progress report. Clinical and Experimental Allergy 32:1128-30