The Malaghan Institute of Medical Research is home to about 80 researchers who are believing the key to fighting diseases lies in harnessing the immune system. Our pioneering research programmes focus on immunology, nutrition & microbiome and cell biology to seek better treatments for diseases including cancer, asthma & allergy, multiple sclerosis and infectious diseases.
The Institute's scientific research publications contain journal articles and academic papers.
Robinson MJ, Prout M, Mearns H, Kyle R, Camberis M, Forbes-Blom EE, Paul WE, Allen CDC, Le Gros G (2017) IL-4 Haploinsufficiency Specifically Impairs IgE Responses against Allergens in Mice. J Immunol.
Dong L-F, Kovarova J, Bajzikova M, Bezawork-Geleta A, Svec D, Endaya B, Sachaphibulkij K, Coelho AR, Sebkova N, Ruzickova A, Tan AS, Kluckova K, Judasova K, Zamecnikova K, Rychtarcikova Z, Gopalan V, Andera L, Sobol M, Yan B, Pattnaik B, Bhatraju N, Truksa J, Stopka P, Hozak P, Lam A, Sedlacek, R, Oliveira P, Kubista M, Agrawal A, Dvorakova-Hortova K, Rohlena J, Berridge MV, Neuzil J (2017) Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells. eLife
Berridge MV, Neuzil J (2017) The mobility of mitochondria: intercellular trafficking in health and disease.Clinical and Experimental Pharmacology and Physiology.
Chandler J, Camberis M, Bouchery T, Blaxter M, Le Gros G, Eccles DA. (2017) Annotated mitochondrial genome with Nanopore R9 signal for Nippostrongylus brasiliensis. F1000Res.
Stuart S, Benton MC, Eccles DA, Sutherland HG, Haupt LM, Lea RA, Griffiths LR. (2017) Gene-centric analysis implicates nuclear encoded mitochondrial protein gene variants in migraine susceptibility. Mol Genet Genomic Med.
Connor LM, Tang SC, Cognard E, Ochiai S, Hilligan KL, Old SI, Pellefigues C, White RF, Patel D, Smith AA, Eccles DA, Lamiable O, McConnell MJ, Ronchese F. (2017) Th2 responses are primed by skin dendritic cells with distinct transcriptional profiles. J Exp Med.
McGrath, A.J, Dolan, C., Cheong-Tilley, S., Herman, D.A.J, Naysmith, B., Zong, F., Galvonas, P, Farrand, K.J., Hermans, I.F., Brimble., M.A., Williams, D., Jin, J. and Tilley, R.D. (2017) Stability of polyelectrolyte-coated iron nanoparticles for T2-weighted magnetic resonance imaging. Journal of Magnetism and Magnetic Materials In press
Brooks, C.R., van Dalen, C.J., Hermans, I.F., Gibson, P.G., Simpson, J.L., and Douwes, J. (2017) Sputum basophils are increased in eosinophilic asthma compared with non-eosinophilic asthma phenotypes. Allergy.
Speir, M., Hermans, I.F. and Weinkove, R. (2017) Engaging natural killer T cells as 'universal helpers' for vaccination. Drugs
Berridge MV, McConnell MJ, Grasso C, Bajzikova M, Kovarova J, Neuzil J (2016) Horizontal transfer of mitochondria between mammalian cells: beyond co-culture approaches. Curr Opin Genetics Dev
Berridge MV, Schneider R, McConnell MJ (2016) Mitochondrial transfer from astrocytes to neurons following ischemic insult: guilt by association? Cell Metab
Bouchery T, Camberis M, Le Gros G (2016) Dye Labeling of Live Nippostrongylus brasiliensis Larvae for Visualization in Host Tissue. Bio-protocol
Camberis M, Bouchery T, Le Gros G (2016) Isolation of Nippostrongylus brasiliensis Larvae from Mouse Lungs. Bio-protocol
Collings S, Thompson O, Hirst E, Goossens L, George A, Weinkove R (2016) Non-Invasive Detection of Anaemia Using Digital Photographs of the Conjunctiva. PLoS One
Eccles DA, Chambers GK, Lea RA (2016) Estimation of Genomic Ancestry in Admixed Populations via Population Sub-sampling. F1000Res
Grasso C, Anaka M, Hofmann O, Sompallae R, Broadley K, Hide W, Berridge MV, Cebon J, Behren A, McConnell MJ (2016) Iterative sorting of CD133+ and CD133- melanoma cells indicates two phenotypically distinct populations. BMC Cancer
Hilligan KL, Connor LM, Schmidt AJ, Ronchese F (2016) Activation-Induced TIM-4 Expression Identifies Differential Responsiveness of Intestinal CD103+ CD11b+ Dendritic Cells to a Mucosal Adjuvant. PLoS One
Le Gros G, Kyle R (2016) The Differentiation and Function of Th2 and Th9 Cells. Encyclopedia of Immunobiology
Price KM, Muirhead KA, Wallace PK (2016) Proliferation by many other names: Monitoring cell cycle progression and cell division by flow cytometry. Cytometry A
Roth I, Campbell H, Rubio C, Vennin C, Wilson M, Wiles A, Williams G, Woolley A, Timpson P, Berridge MV, Fleming N, Baird M, Braithwaite A (2016) The Δ133p53 isoform and its mouse analogue Δ122p53 promote invasion and metastasis involving pro-inflammatory molecules interleukin-6 and CCL2. Oncogene
Schmidt A, Bouchery T, Le Gros G, Price KM (2016) Large Particle Sorting to Isolate Live Parasitic Nematode Eggs. Curr Protoc Cytom
Waghorne CL, Corkran HM, Hunt-Painter AA, Niktab E, Baty JW, Berridge MV, Munkacsi AB, McConnell MJ, Timmer MS, Stocker BL (2016) N,N-Bis(glycityl)amines as anti-cancer drugs. Bioorg Med Chem
Speir M, Kate E, Lawlor KE, Glaser SP, Abraham G, Chow S, Vogrin A, Schulze KE, Schuelein R, O’Reilly LA, Mason K, Hartland EL, Lithgow T, Strasser A, Lessene G, Huang DCS, Vince JE, Naderer T (2016) Eliminating Legionella by inhibiting BCL-XL to induce macrophage apoptosis. Nat Microbiol
Anderson RJ, Compton BJ, Tang C, Authier-Hall A, Hayman CM, Swinerd GW, Kowalczyk R, Harris P, Brimble MA, Larsen DS, Gasser O, Weinkove R, Hermans IF, Painter GF. (2015). NKT Cell-Dependent Glycolipid-Peptide Vaccines with Potent Anti-tumour Activity. Chem. Sci.
Daniels NJ, Hyde E, Ghosh S, Seo K, Price KM, Hoshino K, Kaisho T, Okada T, Ronchese F. (2015) Antigen-specific cytotoxic T lymphocytes target airway CD103+ and CD11b+ dendritic cells to suppress allergic inflammation. Mucosal Immunol.
Hewitson JP, Filbey KJ, Esser-von Bieren J, Camberis M, Schwartz C, Murray J, Reynolds LA, Blair N, Robertson E, Harcus Y, Boon L, Ching-Cheng Huang S, Yang L, Tu L, Miller MJ, Voehringer D, Le Gros G, Harris N, Maizels RM. (2015). Concerted Activity of IgG1 Antibodies and IL-4/IL-25-Dependent Effector Cells Trap Helminth Larvae in the Tissues following Vaccination with Defined Secreted Antigens, Providing Sterile Immunity to Challenge Infection. PLOS Pathogens
Tan AS, Baty JW, Dong LF, Bezawork-Gelata A, Endaya B, Goodwin J, Bajzikova M, Kovarova J, Peterka M; Yan B, Pesdar EA, Sobol M, Filimonenko A, Stuart S, Vondrusova M, Kluckova K; Sachaphibulkij K, Rohlena J, Hozak P, Truska J, Eccles D, Haupt L, Griffiths L, Neuzil J, Berridge MV (2015) Mitochondrial Genome Acquisition Restores Respiratory Function and Tumorigenic Potential of Cancer Cells without Mitochondrial DNA. Cell Metabolism.
Benton MC, Lea RA, Macartney-Coxson D, Bellis C, Carless MA, Curran JE, Hanna M, Eccles DA, Chambers GK, Blangero J, Griffiths JR (2015) Serum bilirubin concentration is modified by UGT1A1 Haplotypes and influences risk of Type-2 diabetes in the Norfolk Island genetic isolate. BMC Genet
Benton MC, Lea RA, Macartney-Coxson D, Hanna M, Eccles DA, Carless MA, Chambers GK, Bellis C, Goring HH, Curran JE, Harper JL, Gibson G, Blangero J, Griffiths LR (2015) A phenomic scan of the Norfolk Island genetic isolate identifies a major pleiotropic effect locus associated with metabolic and renal disorder markers. PLoS Genet
Berridge MV, Dong L, Neuzil J (2015) Mitochondrial DNA in tumor initiation, progression and metastasis: role of horizontal mtDNA transfer. Cancer Res
Berridge MV, Grasso C, Neuzil J (2015) Mitochondrial genome transfer to tumour cells breaks the rules and establishes a new precedent in cancer biology. Mol Cell Oncol
Bouchery T, Kyle R, Camberis M, Shepherd A, Filbey K, Smith A, Harvie M, Painter G, Johnston K, Ferguson P, Jain R, Roediger B, Delahunt B, Weninger W, Forbes-Blom E, Le Gros G (2015) ILC2s and T cells cooperate to ensure maintenance of M2 macrophages for lung immunity against hookworms. Nat Commun
Compton BJ, Tang C, Johnston KA, Osmond TL, Hayman CM, Larsen DS, Hermans IF, Painter GF (2015) Synthesis and Activity of 6″-Deoxy-6″-thio-α-GalCer and Peptide Conjugates. Org Lett
Dalbeth N, Pool B, Shaw OM, Harper JL, Tan P, Franklin C, House ME, Cornish J, Naot D (2015) Role of miR-146a in regulation of the acute inflammatory response to monosodium urate crystals. Ann Rheum Dis
Daniels NJ, Hyde E, Ghosh S, Seo K, Price KM, Hoshino K, Kaisho T, Okada T, Ronchese F (2015) Antigen-specific cytotoxic T lymphocytes target airway CD103+ and CD11b+ dendritic cells to suppress allergic inflammation. Mucosal Immunol
Gibbins JD, Ancelet LR, Osmond TL, Petersen TR, Hermans IF (2015) Splenic dendritic cells involved in cross-tolerance of tumor antigens can play a stimulatory role in adoptive T cell therapy. J Immunother
Hewitson JP, Filbey KJ, Bieren JE, Camberis M, Schwartz C, Murray J, Reynolds LA, Blair N, Robertson E, Harcus Y, Boon L, Huang SC-C, Yang L, Tu Y, Miller MJ, Voehringer D, Le Gros G, Harris N, Maizels RM (2015) Concerted Activity of IgG1 Antibodies and IL-4/IL-25-Dependent Effector Cells Trap Helminth Larvae in the Tissues following Vaccination with Defined Secreted Antigens, Providing Sterile Immunity to Challenge Infection. PLoS Pathog
Ip CL, Loose M, Tyson JR, de Cesare M, Brown BL, Jain M, Leggett RM, Eccles DA, Zalunin V, Urban JM, Piazza P, Bowden RJ, Paten B, Mwaigwisya S, Batty EM, Simpson JT, Snutch TP, Birney E, Buck D, Goodwin S, Jansen HJ, O'Grady J, Olsen HE (2015) MinION Analysis and Reference Consortium, Research Article: MinION Analysis and Reference Consortium: Phase 1 data release and analysis F1000Res
Jang JC, Chen G, Wang SH, Barnes MA, Chung JI, Camberis M, Le Gros G, Cooper PJ, Steel C, Nutman TB, Lazar MA, Nair MG (2015) Macrophage-derived human resistin is induced in multiple helminth infections and promotes inflammatory monocytes and increased parasite burden. PLoS Pathog
Kodar K, Eising S, Khan AA, Steiger S, Harper JL, Timmer MS, Stocker BL (2015) The uptake of trehalose glycolipids by macrophages is independent of Mincle. Chembiochem
Kuhn S, Yang J, Hyde E, Harper J, Kirman J, Ronchese F (2015) L-1beta receptor-dependent priming of anti-tumor CD4 T cells and sustained anti-tumor immunity after peri-tumoral treatment with MSU and mycobacteria. OncoImmunology
Kuhn S, Yang J, Ronchese F (2015) Monocyte-derived dendritic cells are essential for CD8+ T cell activation and anti-tumor responses after local immunotherapy. Front Immunol
Mester B, Bauer B, Wood CE, Hermans IF, Gasser O (2015) Expression of CD1a and Type-1 polarization are dissociated in human monocyte-derived dendritic cells. PLoS One
Osmond TL, Farrand KJ, Painter GF, Ruedl C, Petersen TR, Hermans IF (2015) Activated NKT cells can condition different splenic dendritic cell subsets to respond more effectively to toll-like receptor engagement and enhance cross-priming. J Immunol
Reuter H, Maerz M, Vogg MC, Eccles D, Grifol-Boldu L, Wehner D, Owlarn S, Adell T, Weidinger G, Bartscherer K (2015) β-Catenin-Dependent Control of Positional Information along the AP Body Axis in Planarians Involves a Teashirt Family Member. Cell Rep
Steiger S, Kuhn S, Ronchese F, Harper J (2015) MSU crystals induce upregulation of NK1.1-dependent killing by macrophages and support tumor-resident NK1.1+ monocyte/macrophage populations in anti-tumor therapy. J Immunol
Tan AS, Baty JW, Dong LF, Bezawork-Geleta A, Endaya B, Goodwin J, Bajzikova M, Kovarova J, Peterka M, Yan B, Pesdar EA, Sobo M, Filimonenko A, Stuart S, Vondrusova M, Kluckova K, Sachaphibulkij K, Rohlena J, Hozak P, Truksa J, Eccles D, Haupt LM, Griffiths LR, Neuzil J, Berridge MV (2015) Mitochondrial Genome Acquisition Restores Respiratory Function and Tumorigenic Potential of Cancer Cells without Mitochondrial DNA. Cell Metab
Vieira AT, Macia L, Galvao I, Martins FS, Canesso M CC, Amaral FA, Garcia CC, Maslowski KM, De Leon E, Shim D, Nicoli JR, Harper JL, Teixeira MM, Mackay CR (2015) A Role for Gut Microbiota and the Metabolite-Sensing Receptor GPR43 in a Murine Model of Gout. Arthritis Rheum
Walsh M, White G, Romeril K, Buyck H, Stephens M, Brooks C, Weinkove R (2015) Innate-like T cell profile in myeloma: severe deficiency of Vγ9Vδ2 T cells in aminobisphosphonate-treated patients. Leuk Lymphoma
Weinkove R, Ancelet LR, Gibbins JD, Hermans IF (2015) An adjuvanted whole cell vaccine as postremission immunotherapy for acute leukemia. Oncoimmunology
Castro LM, McConnell MJ, Herst PM (2014) Radiosensitisation by pharmacological ascorbate in glioblastoma multiforme cells, human glial cells, and HUVECs depends on their antioxidant and DNA repair capabilities and is not cancer specific. Free Radic Biol Med & Frontiers in Oncology
Chuluundorj D, Harding SA, Abernethy D, La Flamme AC (2014) Expansion and preferential activation of the CD14+CD16+ monocyte subset during multiple sclerosis. Immunol Cell Biol
Connor LM, Tang SC, Camberis M, Le Gros G, Ronchese F (2014) Helminth–conditioned dendritic cells prime CD4+ T cells to IL-4 production in vivo. J. Immunol
Mearns H, Forbes-Blom EE, Camberis M, Tang SC, Kyle R, Harvie M, Kleinschek MA, Le Gros G IL-25 exhibits disparate roles during Th2-cell differentiation versus effector function. Eur J Immunol
McConnell MJ, Herst PM (2014) Ascorbate combination therapy: new tool in the anticancer toolbox? Sci Transl Med
Ochiai S, Roediger B, Abtin A, Shklovskaya E, Fazekas de St Groth B, Yamane H, Weninger W‡, Le Gros G, Ronchese F (2014) CD326loCD103loCD11blo dermal dendritic cells are activated by Thymic Stromal Lymphopoietin during contact sensitization in mice. J Immunol.
Shaw OM, Pool B, Dalbeth N, Harper JL The effect of diet-induced obesity on the inflammatory phenotype of non-adipose-resident macrophages in an in vivo model of gout. Rheumatology (Oxford)
Shaw OM, Steiger S, Liu X, Hamilton JA, Harper JL GM-CSF drives MSU crystal-induced inflammatory macrophage differentiation and NLRP3 inflammasome upregulation in vivo. Arthritis Rheumatol
Steiger S, Harper JL (2014) Mechanisms of spontaneous resolution of acute gouty inflammation. Curr Rheumatol Rep
Tan AS, Baty JW, Berridge MV (2014) The role of mitochondrial electron transport in tumorigenesis and metastasis. Biochim Biophys Acta
White M, Webster G, O’Sullivan D, Stone S, La Flamme AC (2014) Targeting innate receptors with MIS416 reshapes Th responses and suppresses CNS disease in a mouse model of multiple sclerosis. PLoS One
Anderson RJ, Tang C, Daniels NJ, Compton BJ, Hayman CM, Johnston KA, Knight DA, Gasser O, Poyntz HC, Ferguson PM, Larsen DS, Ronchese F, Painter GF, Hermans, IF. ‘A novel synthetic self-adjuvanting lipopeptide vaccine to induce cytotoxic T lymphocytes that suppress allergic disease’. Nature Chemical Biology.
Authier A, Farrand KJ, Broadley KWR, Stone S, Hunn MK, Ancelet LR, McConnell MJ, Hermans IF. (2014) Enhanced immunosuppression by therapy-exposed glioblastoma multiforme tumor cells. Int J Cancer.
Bouchery T, Kyle R, Ronchese F, Le Gos G. (2014) The differentiation of CD4+ T-helper cell subsets in the context of helminth parasite infection. Review article. Frontiers Immunol.
Castro LM, McConnell MJ, Herst PM. (2014) Radiosensitisation by pharmacological ascorbate in glioblastoma multiforme cells, human glial cells, and HUVECs depends on their antioxidant and DNA repair capabilities and is not cancer specific. Free.Radic.Biol.Med.
Connor LM, Tang SC, Camberis M, Le Gros G, Ronchese F (2014) Helminth–conditioned dendritic cells prime CD4+ T cells to IL-4 production in vivo. J. Immunol.
Fleming S, Yannakou C K, Haeusler GM, Clark J, Grigg A, Heath CH, Bajel A, van Hal SJ, Chen S, Milliken ST, Morrissey CO, Tam. J. Szer CS, Weinkove R, Slavin M. (2014) Consensus guidelines for antifungal prophylaxis in haematological malignancy and haemopoietic stem cell transplantation. Intern Med J.
Grasso C, Fabre MS, Collis SV, Castro ML, Field CS, Schleich N, McConnell MJ, Herst PM. (2014). Pharmacological doses of daily ascorbate protect tumors from radiation damage after a single dose of radiation in an intracranial mouse glioma model. Front Oncol.
Gibbins JD, Ancelet LR, Weinkove R, Compton BJ, Painter GF,, Petersen TR, Hermans IF. (2014). An autologous leukemia cell vaccine prevents murine acute leukemia relapse after cytarabine treatment. Blood.
Hunn MK, Bauer E, Wood CE, Gasser O, Dzhelali M, Ancelet LR, Mester B, Sharples KJ, Findlay MP, Hamilton DA, and Hermans IF. (2014). Dendritic cell vaccination combined with temozolomide retreatment: Results of a phase I trial in patients with recurrent glioblastoma multiforme . Journal of Neuro-Oncology.
Ochiai S, Roediger B, Abtin A, Shklovskaya E,Fazekas de St Groth B, Yamane H, Weninger‡ W, Le Gros G, Ronchese.F. (2014). CD326loCD103loCD11blo dermal dendritic cells are activated by Thymic Stromal Lymphopoietin during contact sensitization in mice. J Immunol.
Prendergast KA, Osmond TL, Ochiai S, Hermans IF and Kirman JR. (2014). Sustained in vivo depletion of splenic langerin+ CD8<alpha>+ dendritic cells is well-tolerated by lang-DTREGFP mice. J Immunol. Methods
Mecozzi VJ, Berman DE, Simoes S, Vetanovetz C, Awal MR, Patel VM, Schneider RT, Petsko GA, Ringe D, Small SA. (2014). Pharmacological chaperones stabilize retromer to limit APP processing. N. Chem. Bio.
Nyanhanda T, Gould EM, McGhie T, Shaw OM, Harper JL, Hurst RD. (2014) Blackcurrant polyphenolic cultivar extracts suppress CCL26 secretion from alveolar epithelial cells. Food and Function.
Petersen TR, Knight DA, Ching-Wen T, Osmond TL, Hermans IF. (2014) "Batf3-independent langerin- CX3CR1- CD8α+ splenic DCs represent a precursor for classical cross-presenting CD8α+ DC. Journal of Leukocyte Biology
Roediger B, Kyle R, Le Gros G, Weninger W. (2014) Dermal group 2 innate lymphoid cells in atopic dermatitis and allergy. Curr. Op. Immunol.
Shaw OM, Pool B, Dalbeth N, Harper JL (2014) The effect of diet-induced obesity on the inflammatory phenotype of non-adipose-resident macrophages in an in vivo model of gout. Rheumatol.
Shaw OM, Steiger S, Liu X, Hamilton JA, Harper JL (2014) Granulocyte-Macrophage Colony-Stimulating factor drives monosodium urate monohydrate crystal-induced inflammatory macrophage differentiation and NLRP3 inflammasome up-regulation in an in vivo mouse model. Arthritis & Rheumatol.
Sotillo J, Sanchez-Flores A, Cantacessi C, Harcus Y, Pickering D, Bouchery T, Camberis M, Tang SC, Giacomin P, Mulvenna J, Mitreva M, Berriman M, Le Gros G, Maizels RM, Loukas A. (2014) Secreted Proteomes of Different Developmental Stages of the Gastrointestinal Nematode Nippostrongylus brasiliensis. Molecular & Cellular Proteomics.
Timmer MSM, Sauvageau J, Foster AJ, Ryan J, Lagutin K, Shaw O, Harper JL, Sims IM, Stocker BL. (2014) Discovery of Lipids from B. longum subsp. infantis using Whole Cell MALDI Analysis. J. Org. Chem.
Berridge MV, Dong L, Neuzil J. (2015) Mitochondrial DNA in tumour initiation, progression and metastasis: role of horizontal mtDNA transfer. Cancer Research
Weinkove R, Bailey M, Bellomo R, Saxena MK, Tam CS, Pilcher DV, Beasley D and Young PJ. (2014) Association between early peak temperature and mortality in neutropenic sepsis. Ann Hematol.
Ataera H, Simkins HM, Hyde E, Yang J, Hermans IF, Petersen TR, Ronchese F The control of CD8+ T cell responses is preserved in perforin-deficient mice and released by depletion of CD4+ CD25+ regulatory T cells. J Leukoc Biol
Brooks CR, van Dalen CJ, Hermans IF, Douwes J (2013) Identifying leukocyte populations in fresh and cryopreserved sputum using flow cytometry. Cytometry B Clin Cytom
Camberis M, Prout M, Tang SC, Forbes-Blom E, Robinson M, Kyle R, Belkaid Y, Paul W, Le Gros G (2013) Evaluating the in vivo Th2 priming potential among common allergens. J Immunol Methods
Corkran HM,Munneke S, Dangerfield EM, Stocker BL,Timmer MSM Applications and limitations of the I2-mediated carbamate annulation for the synthesis of piperidines: 5- versus 6-membered cyclisation. J Org Chem
Ferguson PM, Feindel KW, Slocombe A, MacKay M, Wignall T, Delahunt B, Tilley RD, Hermans IF (2013) Strongly magnetic iron nanoparticles improve the diagnosis of small tumours in the reticuloendothelial system by magnetic resonance imaging. PLoS One
Ferguson PM, Slocombe A, Tilley RD, Hermans IF (2013) Using magnetic resonance imaging to evaluate dendritic cell-based vaccination. PLoS One
Grainger R, McLaughlin RJ, Harrison AA, Harper JL (2013) Hyperuricaemia elevates circulating CCL2 levels and primes monocyte trafficking in subjects with inter-critical gout. Rheumatology (Oxford)
Grasso C, Larsen L, McConnell M, Smith RA, Berridge MV (2013) Anti-leukemic activity of ubiquinone-based compounds targeting trans-plasma membrane electron transport. J Med Chem
Harvie M, Camberis M, Le Gros G (2013) Development of CD4 T cell dependent immunity against N. brasiliensis infection. Front Immunol
Herst PM, Berridge MV (2013) Cell hierarchy, metabolic flexibility and systems approaches to cancer treatment. Curr Pharm Biotechnol
Hunn MK, Hermans IF (2013) Exploiting invariant NKT cells to promote T cell responses to cancer vaccines. Oncoimmunology
Johnston LR, Larsen PD, La Flamme AC, Harding SA (2013) Methodological considerations for the assessment of ADP induced platelet aggregation using the Multiplate® analyser. Platelets
Johnston LR, Larsen PD, La Flamme AC, Michel JM, Harding SA (2013) Suboptimal response to clopidogrel and the effect of prasugrel in acute coronary syndromes. Int J Cardiol
Khan AA, Kamena F, Timmer MSM, Stocker BL (2013) Development of a benzophenone and alkyne functionalised trehalose probe to study trehalose dimycolate binding proteins. Org Biomol Chem
Kuhn S, Hyde EJ, Yang J, Rich FJ, Harper JL, Kirman JR, Ronchese F Increased numbers of monocyte-derived dendritic cells during successful tumor immunotherapy with immune-activating agents. J Immunol
Prendergast KA, Kirman JR (2013) Dendritic cell subsets in mycobacterial infection: control of bacterial growth and T cell responses. Tuberculosis (Edinb)
Roediger B, Kyle R, Ho Yip K, Sumaria N, Guy TV, Kim BS, Mitchell AJ, Tay SS, Jain R, Forbes-Blom E, Chen X, Tong PL, Bolton HA, Artis D, Paul WE, Fazekas de St Groth B, Grimbaldeston MA, Le Gros G, Weninger W (2013) Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells. Nat Immunol
Roohullah A, Moniwa A, Wood C, Humble M, Balm M, Carter J, Weinkove R Imipenem versus piperacillin/tazobactam for empiric treatment of febrile neutropenia in adults. Intern Med J, (in press)
Shaw OM, Harper JL An efficient single prime protocol for the induction of antigen-induced airways inflammation. J Immunol Methods, (in press)
Slaney CY, Toker A, Fraser JD, Harper JL, Bäckström BT (2013) A modified superantigen rescues Ly6G-CD11b+ blood monocyte suppressor function and suppresses antigen-specific inflammation in EAE. Autoimmunity
Steiger S, Harper JL (2013) Neutrophil cannibalism triggers transforming growth factor β1 production and self-regulation of neutrophil inflammatory function in monosodium urate monohydrate crystal-induced inflammation in mice. Arthritis Rheum
Stocker BL, Jongkees SA, Win-Mason AL, Dangerfield EM, Withers SG, Timmer MS (2013) The ‘mirror-image’ postulate as a guide to the selection and evaluation of pyrrolidines as α-L-fucosidase inhibitors. Carbohydrate Res
Stocker BL, Timmer MS (2013) Chemical tools for studying the biological function of glycolipids. Chembiochem
Stocker BL, Timmer MS Trehalose diesters, lipoteichoic acids and α-GalCer: using chemistry to understand immunology. Carbohydrate Res
van Panhuys N, Camberis M, Yamada M, Tegoshi T, Arizono N, Le Gros G (2013) Mucosal trapping and degradation of Nippostrongylus brasiliensis occurs in the absence of STAT6. Parasitology
Weinkove R, Brooks CR, Carter JM, Hermans IF, Ronchese F (2013) Functional invariant natural killer T cell and CD1d axis in chronic lymphocytic leukemia: implications for immunotherapy. Haematologica
Weinkove R, Brooks C, Carter JM, Hermans IF, Ronchese F Efficient depletion of chronic lymphocytic leukemia B cells using serial rounds of immunomagnetic depletion. J Immunol Methods
Weinkove R, Clay J, Wood C (2013) Temperature management in haematology patients with febrile neutropenia: a practice survey. NZ Med J
Ataera H, Simkins HM, Hyde E, Yang J, Hermans IF, Petersen TR, Ronchese F (2013) The control of CD8+ T cell responses is preserved in perforin-deficient mice and released by depletion of CD4+ CD25+ regulatory T cells. J Leukoc Biol,
Benton MC, Lea RA, Macartney-Coxson D, Carless MA, Goring HH, Bellis C, Hanna M, Eccles D, Chambers GK, Curran JE, Harper JL, Blangero J, Griffiths LR (2013) Mapping eQTLs in the Norfolk Island genetic isolate identifies candidate genes for CVD risk traits. Am J Hum Genet
Kim S, Karasuyama H, Lopez AF, Ouyang W, Li X, Le Gros G, Min B (2013) IL-4 derived from non-T cells induces basophil- and IL-3-independent Th2 immune responses. Immune Netw
Kuhn S, Hyde EJ, Yang J, Rich FJ, Harper JL, Kirman JR, Ronchese F (2013) Increased numbers of monocyte-derived dendritic cells during successful tumor immunotherapy with immune-activating agents. J Immunol
Kuhn S, Ronchese F (2013) Monocyte-derived dendritic cells: Emerging players in the antitumor immune response. Oncoimmunology,
O’Sullivan D, Miller JH, Northcote PT, La Flamme AC (2013) Microtubule-stabilizing agents delay the onset of EAE through inhibition of migration. Immunol Cell Biol
Roohullah A, Moniwa A, Wood C, Humble M, Balm M, Carter J, Weinkove R (2013) Imipenem versus piperacillin/tazobactam for empiric treatment of febrile neutropenia in adults. Intern Med J
Shaw OM, Harper JL (2013) An efficient single prime protocol for the induction of antigen-induced airways inflammation. J Immunol Methods
Weinkove R, Brooks C, Carter J, Hermans I, Ronchese F (2013) Efficient depletion of chronic lymphocytic leukemia B cells using serial rounds of immunomagnetic depletion. J Immunol Methods
Weinkove R, Dickson M, Eliadou E, Stace NH, Goossens L, Ferguson P (2013) Fever and pancytopenia in a patient with Crohn's disease. Gut
Ancelet LR, Aldwell FE, Rich FJ, Kirman JR (2012) Oral vaccination with lipid-formulated BCG induces a long-lived, multifunctional CD4+ T cell memory immune response. PLoS One
Ancelet L, Rich FJ, Delahunt B, Kirman JR (2012) Dissecting memory T cell responses to TB: Concerns using adoptive transfer into immunodeficient mice. Tuberculosis (Edinb)
Dickgreber N, Farrand KJ, van Panhuys N, Knight DA, McKee SJ, Chong ML, Miranda-Hernandez S, Baxter AG, Locksley RM, Le Gros G, Hermans IF (2012) Immature NKT cells pass through a stage of developmentally programmed innate IL-4 secretion. J Leukoc Biol
Herbst T, Esser J, Prati M, Kulagin M, Stettler R, Zaiss MM, Hewitson JP, Merky P, Verbeek JS, Bourquin C, Camberis M, Prout M, Maizels RM, Le Gros G, Harris NL (2012) Antibodies and IL-3 support helminth-induced basophil expansion. Proc Natl Acad Sci US
Hunn MK, Farrand KJ, Broadley KW, Weinkove R, Ferguson P, Miller RJ, Field CS, Petersen T, McConnell MJ, Hermans IF (2012) Vaccination with irradiated tumor cells pulsed with an adjuvant that stimulates NKT cells is an effective treatment for glioma. Clin Cancer Res
Kanakkanthara A, Rawson P, Northcote PT, Miller JH (2012) Acquired resistance to peloruside A and laulimalide is associated with downregulation of vimentin in human ovarian carcinoma cells. Pharm Res
La Flamme AC, Kharkrang M, Stone S, Mirmoeini S, Chuluundorj D, Kyle R (2012) Type II-activated murine macrophages produce IL-4. PLoS One
Lim SN, Kuhn S, Hyde E, Ronchese F (2012) Combined TLR stimulation with Pam3Cys and Poly I:C enhances Flt3-ligand dendritic cell activation for tumor immunotherapy. J Immunother
Liu X, Chia E, Shaw OM, Martin WJ, Harper JL (2012) Rapid CCL2 release by membrane stromal cells initiates MSU crystal-induced monocyte recruitment in a peritoneal model of gouty inflammation. Eur J Inflamm
Ma Z-I, Lim SN, Qin JS, Yang J, Enomoto N, Ruedl C, Ronchese F (2012) Murine CD4+ T cell responses are inhibited by cytotoxic T cell-mediated killing of dendritic cells and are restored by antigen transfer. PLoS One
Ma Z-I, Yang J, Qin JS, Richter A, Perret R, El-Deiry WS, Finnberg N, Ronchese F (2012) Inefficient boosting of antitumour CD8(+) T cells by dendritic-cell vaccines is rescued by restricting T-cell cytotoxic functions. Oncoimmunology
Parker S, La Flamme A, Salinas I (2012) The ontogeny of New Zealand groper (Polyprion oxygeneios) lymphoid organs and IgM. Dev Comp Immunol
Paterson DB, Poonam P, Bennett NC, Peszynski RI, Van Beekhuizen MJ, Jasperse ML, Herst PM (2012) Randomized intra-patient controlled trial of mepilex lite dressings versus aqueous cream in managing radiation-induced skin reactions post-mastectomy. J Cancer Sci Ther
Rawson P, Stockum C, Peng L, Manivannan B, Lehnert K, Ward HE, Berry SD, Davis SR, Snell RG, McLauchlan D, Jordan TW (2012) Metabolic proteomics of the liver and mammary gland during lactation. J Proteomics
Rich FJ, Kuhn S, Hyde EJ, Harper JL, Ronchese F, Kirman JR (2012) Induction of T cell responses and recruitment of an inflammatory dendritic cell subset following tumour immunotherapy with Mycobacterium smegmatis. Cancer Immunol Immunother
Robinson M, McConnell MJ, Le Gros G (2012) How epigenetic imprinting contributes to stabilizing the Th2 phenotype. Immunol Cell Biol
Sauvageau J, Foster AJ, Khan AA, Chee SH, Sims IM, Timmer MSM, Stocker BL (2012) Synthesis and biological activity of the LTA glycolipid anchor from Streptocossus sp. DSM 8747. Chembiochem
Smit AM, Strabala TJ, Peng L, Rawson P, Lloyd-Jones G, Jordan TW (2012) Proteomic phenotyping of Novosphingobium nitrogenifigens reveals a robust capacity for simultaneous nitrogen fixation, polyhydroxyalkanoate production, and resistance to reactive oxygen species. Appl Environ Microbiol
Williams JM, Young P, Pilcher J, Weatherall M, Miller JH, Beasley R, La Flamme AC (2012) Remote ischaemic preconditioning does not alter perioperative cytokine production in high-risk cardiac surgery. Heart Asia